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1

A deeper look at mitochondrial dynamics in Parkinson's disease

Cristina Guardia-Laguarta

Journal:

Movement Disorders

Year:

2012

Language:

english

File:

PDF, 676 KB

english, 2012

2

Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease

Cooper, O., Seo, H., Andrabi, S., Guardia-Laguarta, C., Graziotto, J., Sundberg, M., McLean, J. R., Carrillo-Reid, L., Xie, Z., Osborn, T., Hargus, G., Deleidi, M., Lawson, T., Bogetofte, H., Perez-To

Journal:

Science Translational Medicine

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

3

Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

Francesc X. Guix, Tina Wahle, Kristel Vennekens, An Snellinx, Lucía Chávez-Gutiérrez, Gerard Ill-Raga, Eva Ramos-Fernandez, Cristina Guardia-Laguarta, Alberto Lleó, Muriel Arimon, Oksana Berezovska, F

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 993 KB

english, 2012

4

A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo

L. Serenó, M. Coma, M. Rodríguez, P. Sánchez-Ferrer, M.B. Sánchez, I. Gich, J.M. Agulló, M. Pérez, J. Avila, C. Guardia-Laguarta, J. Clarimón, A. Lleó, T. Gómez-Isla

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 1.47 MB

english, 2009

5

Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease

M. Coma, L. Serenó, B. Da Rocha-Souto, T.C. Scotton, J. España, M.B. Sánchez, M. Rodríguez, J. Agulló, C. Guardia-Laguarta, M. Garcia-Alloza, L.A. Borrelli, J. Clarimón, A. Lleó, B.J. Bacskai, C.A. Sa

Journal:

Neurobiology of Disease

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

6

The pathogenic I716F amyloid precursor protein (APP) mutation leads to a reduced protein processing and a very aggressive early-onset Alzheimer's disease

Cristina Guardia-Laguarta, Marta Pera, Jordi Clarimon, Albert Llado, Raquel Sánchez-Valle, Jose Luis Molinuevo, Teresa Gómez-Isla, Rafael Blesa, Isidre Ferrer, Alberto Lleo

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

7

Mild cholesterol depletion reduces amyloid-β production by impairing APP trafficking to the cell surface

Cristina Guardia-Laguarta, Mireia Coma, Marta Pera, Jordi Clarimón, Lidia Sereno, José M. Agulló, Laura Molina-Porcel, Eduard Gallardo, Amy Deng, Oksana Berezovska, Bradley T. Hyman, Rafael Blesa, Ter

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 629 KB

english, 2009

8

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

Marta Pera, Daniel Alcolea, Raquel Sánchez-Valle, Cristina Guardia-Laguarta, Martí Colom-Cadena, Nahuai Badiola, Marc Suárez-Calvet, Albert Lladó, Alvaro A. Barrera-Ocampo, Diego Sepulveda-Falla, Rafa

Journal:

Acta Neuropathologica

Year:

2013

Language:

english

File:

PDF, 663 KB

english, 2013

9

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

Area-Gomez, Estela, del Carmen Lara Castillo, Maria, Tambini, Marc D, Guardia-Laguarta, Cristina, de Groof, Ad J C, Madra, Moneek, Ikenouchi, Junichi, Umeda, Masato, Bird, Thomas D, Sturley, Stephen L

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 3.37 MB

english, 2012

10

-Synuclein Is Localized to Mitochondria-Associated ER Membranes

Guardia-Laguarta, C., Area-Gomez, E., Rub, C., Liu, Y., Magrane, J., Becker, D., Voos, W., Schon, E. A., Przedborski, S.

Journal:

Journal of Neuroscience

Year:

2014

Language:

english

File:

PDF, 3.96 MB

english, 2014

11

Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production

Suárez-Calvet, Marc, Belbin, Olivia, Pera, Marta, Badiola, Nahuai, Magrané, Jordi, Guardia-Laguarta, Cristina, Muñoz, Laia, Colom-Cadena, Martí, Clarimón, Jordi, Lleó, Alberto

Journal:

Journal of Neurochemistry

Year:

2014

Language:

english

File:

PDF, 498 KB

english, 2014

12

Mutations in CODON 716 of the amyloid precursor protein differentially affect APP processing

Suarez-Calvet, Marc, Guardia-Laguarta, Cristina, Pera, Marta, Badiola, Nahuai, Alcolea, Daniel, Setó-Salvia, Núria, Dols, Oriol, Magrané, Jordi, Clarimón, Jordi, Blesa, Rafael, Lleó, Alberto

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 142 KB

english, 2011

13

P4-210: Effects of mild cholesterol depletion on APP processing and gamma-secretase

Guardia-Laguarta, Cristina, Coma, Mireia, Clarimon, Jordi, Sereno, Lidia, Agullo, Jose Manuel, Molina, Laura, Blesa, Rafael, Gomez-Isla, Teresa, Lleo, Alberto

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

14

-Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1

Espana, J., Valero, J., Minano-Molina, A. J., Masgrau, R., Martin, E., Guardia-Laguarta, C., Lleo, A., Gimenez-Llort, L., Rodriguez-Alvarez, J., Saura, C. A.

Journal:

Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 1.66 MB

english, 2010

15

Prognostic Value of Plasma -Amyloid Levels in Patients With Acute Intracerebral Hemorrhage

Marti-Fabregas, J., Delgado-Mederos, R., Marin, R., de la Ossa, N. P., de Lecinana, M. A., Rodriguez-Yanez, M., Sanahuja, J., Purroy, F., De Arce, A. M., Carrera, D., Dinia, L., Guardia-Laguarta, C.,

Journal:

Year:

2014

Language:

english

File:

PDF, 606 KB

english, 2014

16

Early-Onset Familial Lewy Body Dementia With Extensive Tauopathy: A Clinical, Genetic, and Neuropathological Study

Clarimón, Jordi, Molina-Porcel, Laura, Gómez-Isla, Teresa, Blesa, Rafael, Guardia-Laguarta, Cristina, González-Neira, Anna, Estorch, Montserrat, Ma Grau, Josep, Barraquer, Lluís, Roig, Carles, Ferrer,

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2009

Language:

english

File:

PDF, 1.08 MB

english, 2009

17

Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation

Guardia-Laguarta, Cristina, Pera, Marta, Clarimón, Jordi, Molinuevo, José Luis, Sànchez-Valle, Raquel, Lladó, Albert, Coma, Mireia, Gómez-Isla, Teresa, Blesa, Rafael, Ferrer, Isidre, Lleó, Alberto

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2010

Language:

english

File:

PDF, 774 KB

english, 2010

18

A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication

Guardia-Laguarta, Cristina, Area-Gomez, Estela, Schon, Eric A., Przedborski, Serge

Journal:

Movement Disorders

Year:

2015

Language:

english

File:

PDF, 427 KB

english, 2015

19

ApoE4 upregulates the activity of mitochondria-associated ER membranes

Tambini, M. D., Pera, M., Kanter, E., Yang, H., Guardia-Laguarta, C., Holtzman, D., Sulzer, D., Area-Gomez, E., Schon, E. A.

Journal:

Year:

2016

Language:

english

File:

PDF, 920 KB

english, 2016

20

The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form

Liu, Yuhui, Guardia-Laguarta, Cristina, Yin, Jiang, Erdjument-Bromage, Hediye, Martin, Brittany, James, Michael, Jiang, Xuejun, Przedborski, Serge

Journal:

Year:

2017

Language:

english

File:

PDF, 2.91 MB

english, 2017

21

Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy

Badiola, Nahuai, de Oliveira, Rita Machado, Herrera, Federico, Guardia-Laguarta, Cristina, Gonçalves, Susana A., Pera, Marta, Suárez-Calvet, Marc, Clarimon, Jordi, Outeiro, Tiago Fleming, Lleó, Albert

Journal:

Year:

2011

Language:

english

File:

PDF, 493 KB

english, 2011

22

Novel subcellular localization for Î±-synuclein: possible functional consequences

Guardia-Laguarta, Cristina, Area-Gomez, Estela, Schon, Eric A., Przedborski, Serge

Journal:

Frontiers in Neuroanatomy

Year:

2015

Language:

english

File:

PDF, 584 KB

english, 2015

23

MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

Larrea, Delfina, Pera, Marta, Gonelli, Adriano, Cabrera, Ruben Quintana, Akman, H Orhan, Guardia-Laguarta, Cristina, Velasco, Kevin R, Area-Gomez, Estela, dal Bello, Federica, De Stefani, Diego, Horva

Journal:

Human Molecular Genetics

Year:

2019

Language:

english

File:

PDF, 3.29 MB

english, 2019

24

The fat brain

Montesinos, Jorge, Guardia-Laguarta, Cristina, Area-Gomez, Estela

Journal:

Current Opinion in Clinical Nutrition & Metabolic Care

Year:

2020

File:

PDF, 793 KB

2020

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